Targeted mutagenesis of simian virus 40 DNA mediated by a triple helix-forming oligonucleotide.
Triple-helical DNA can be formed by oligonucleotides that bind as third strands of DNA in a sequence-specific manner in the major groove in homopurine/homopyrimidine stretches in duplex DNA. Such triple helix-forming oligonucleotides have been used to inhibit gene expression by blocking transcriptio...
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| Udgivet i: | J Virol |
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| Principais autores: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology (ASM)
1993
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC238196/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8230456/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.67.12.7324-7331.1993 |
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