Targeted mutagenesis in mammalian cells mediated by intracellular triple helix formation.

As an alternative to standard gene transfer techniques for genetic manipulation, we have investigated the use of triple helix-forming oligonucleotides to target mutations to selected genes within mammalian cells. By treating monkey COS cells with oligonucleotides linked to psoralen, we have generate...

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Bibliographic Details

Published in:	Mol Cell Biol
Main Authors:	Wang, G, Levy, D D, Seidman, M M, Glazer, P M
Format:	Artigo
Language:	Inglês
Published:	Taylor & Francis 1995
Subjects:	Research Article
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC230400/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7862165/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.15.3.1759
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