Targeted mutagenesis in mammalian cells mediated by intracellular triple helix formation.
As an alternative to standard gene transfer techniques for genetic manipulation, we have investigated the use of triple helix-forming oligonucleotides to target mutations to selected genes within mammalian cells. By treating monkey COS cells with oligonucleotides linked to psoralen, we have generate...
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| Publicado no: | Mol Cell Biol |
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| Principais autores: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
1995
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC230400/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7862165/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.15.3.1759 |
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