Targeted mutagenesis in mammalian cells mediated by intracellular triple helix formation.

As an alternative to standard gene transfer techniques for genetic manipulation, we have investigated the use of triple helix-forming oligonucleotides to target mutations to selected genes within mammalian cells. By treating monkey COS cells with oligonucleotides linked to psoralen, we have generate...

Ausführliche Beschreibung

Bibliografische Detailangaben

Veröffentlicht in:	Mol Cell Biol
Hauptverfasser:	Wang, G, Levy, D D, Seidman, M M, Glazer, P M
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Taylor & Francis 1995
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC230400/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7862165/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.15.3.1759
Tags:	Tag hinzufügen Keine Tags, Fügen Sie das erste Tag hinzu!