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Potential role of cathepsin K in the pathophysiology of mucopolysaccharidoses
Cathepsin K, a papain-like cysteine protease, is highly expressed in osteoclasts and plays a critical role in bone resorption. Dysfunction of the enzyme leads to various skeletal abnormalities. The recent knowledge that the collagenolytic activity of cathepsin K depends on interactions with bone and...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3103771/ https://ncbi.nlm.nih.gov/pubmed/21629671 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/PRM-2010-0116 |
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