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Cathepsin K Activity-dependent Regulation of Osteoclast Actin Ring Formation and Bone Resorption

Cathepsin K is responsible for the degradation of type I collagen in osteoclast-mediated bone resorption. Collagen fragments are known to be biologically active in a number of cell types. Here, we investigate their potential to regulate osteoclast activity. Mature murine osteoclasts were seeded on t...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Wilson, Susan R., Peters, Christoph, Saftig, Paul, Brömme, Dieter
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2629117/
https://ncbi.nlm.nih.gov/pubmed/19028686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M805280200
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