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Cathepsins in the Pathophysiology of Mucopolysaccharidoses: New Perspectives for Therapy

Cathepsins (CTSs) are ubiquitously expressed proteases normally found in the endolysosomal compartment where they mediate protein degradation and turnover. However, CTSs are also found in the cytoplasm, nucleus, and extracellular matrix where they actively participate in cell signaling, protein proc...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: De Pasquale, Valeria, Moles, Anna, Pavone, Luigi Michele
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7227001/
https://ncbi.nlm.nih.gov/pubmed/32326609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9040979
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