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Assessing the benefits of using mate-pairs to resolve repeats in de novo short-read prokaryotic assemblies

BACKGROUND: Next-generation sequencing technologies allow genomes to be sequenced more quickly and less expensively than ever before. However, as sequencing technology has improved, the difficulty of de novo genome assembly has increased, due in large part to the shorter reads generated by the new t...

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書誌詳細
主要な著者: Wetzel, Joshua, Kingsford, Carl, Pop, Mihai
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3103447/
https://ncbi.nlm.nih.gov/pubmed/21486487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-12-95
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