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Assembly complexity of prokaryotic genomes using short reads

BACKGROUND: De Bruijn graphs are a theoretical framework underlying several modern genome assembly programs, especially those that deal with very short reads. We describe an application of de Bruijn graphs to analyze the global repeat structure of prokaryotic genomes. RESULTS: We provide the first s...

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Detalhes bibliográficos
Main Authors: Kingsford, Carl, Schatz, Michael C, Pop, Mihai
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2821320/
https://ncbi.nlm.nih.gov/pubmed/20064276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-11-21
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