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Assessing the benefits of using mate-pairs to resolve repeats in de novo short-read prokaryotic assemblies

BACKGROUND: Next-generation sequencing technologies allow genomes to be sequenced more quickly and less expensively than ever before. However, as sequencing technology has improved, the difficulty of de novo genome assembly has increased, due in large part to the shorter reads generated by the new t...

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Detalhes bibliográficos
Main Authors: Wetzel, Joshua, Kingsford, Carl, Pop, Mihai
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3103447/
https://ncbi.nlm.nih.gov/pubmed/21486487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-12-95
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