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De novo fragment assembly with short mate-paired reads: Does the read length matter?

Increasing read length is currently viewed as the crucial condition for fragment assembly with next-generation sequencing technologies. However, introducing mate-paired reads (separated by a gap of length, GapLength) opens a possibility to transform short mate-pairs into long mate-reads of length ≈...

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Detalhes bibliográficos
Main Authors: Chaisson, Mark J., Brinza, Dumitru, Pevzner, Pavel A.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2652199/
https://ncbi.nlm.nih.gov/pubmed/19056694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.079053.108
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