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De novo fragment assembly with short mate-paired reads: Does the read length matter?

Increasing read length is currently viewed as the crucial condition for fragment assembly with next-generation sequencing technologies. However, introducing mate-paired reads (separated by a gap of length, GapLength) opens a possibility to transform short mate-pairs into long mate-reads of length ≈...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Chaisson, Mark J., Brinza, Dumitru, Pevzner, Pavel A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Cold Spring Harbor Laboratory Press 2009
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2652199/
https://ncbi.nlm.nih.gov/pubmed/19056694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.079053.108
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