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Local De Novo Assembly of RAD Paired-End Contigs Using Short Sequencing Reads
Despite the power of massively parallel sequencing platforms, a drawback is the short length of the sequence reads produced. We demonstrate that short reads can be locally assembled into longer contigs using paired-end sequencing of restriction-site associated DNA (RAD-PE) fragments. We use this RAD...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3076424/ https://ncbi.nlm.nih.gov/pubmed/21541009 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0018561 |
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