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The nuclear RNA polymerase II surveillance system targets polymerase III transcripts

A key question in nuclear RNA surveillance is how target RNAs are recognized. To address this, we identified in vivo binding sites for nuclear RNA surveillance factors, Nrd1, Nab3 and the Trf4/5–Air1/2–Mtr4 polyadenylation (TRAMP) complex poly(A) polymerase Trf4, by UV crosslinking. Hit clusters wer...

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Bibliografski detalji
Glavni autori: Wlotzka, Wiebke, Kudla, Grzegorz, Granneman, Sander, Tollervey, David
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3102002/
https://ncbi.nlm.nih.gov/pubmed/21460797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.97
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