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Transcriptome-wide Analysis of Exosome Targets

The exosome plays major roles in RNA processing and surveillance but the in vivo target range and substrate acquisition mechanisms remain unclear. Here we apply in vivo RNA crosslinking (CRAC) to the nucleases (Rrp44, Rrp6), two structural subunits (Rrp41, Csl4) and a cofactor (Trf4) of the yeast ex...

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Autors principals: Schneider, Claudia, Kudla, Grzegorz, Wlotzka, Wiebke, Tuck, Alex, Tollervey, David
Format: Artigo
Idioma:Inglês
Publicat: Cell Press 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3526797/
https://ncbi.nlm.nih.gov/pubmed/23000172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2012.08.013
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