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Transcriptome-wide analysis of alternative routes for RNA substrates into the exosome complex

The RNA exosome complex functions in both the accurate processing and rapid degradation of many classes of RNA. Functional and structural analyses indicate that RNA can either be threaded through the central channel of the exosome or more directly access the active sites of the ribonucleases Rrp44 a...

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Detalles Bibliográficos
Publicado en:PLoS Genet
Main Authors: Delan-Forino, Clémentine, Schneider, Claudia, Tollervey, David
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5389853/
https://ncbi.nlm.nih.gov/pubmed/28355211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006699
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