Transcriptome-wide Analysis of Exosome Targets

The exosome plays major roles in RNA processing and surveillance but the in vivo target range and substrate acquisition mechanisms remain unclear. Here we apply in vivo RNA crosslinking (CRAC) to the nucleases (Rrp44, Rrp6), two structural subunits (Rrp41, Csl4) and a cofactor (Trf4) of the yeast ex...

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Bibliographic Details
Main Authors: Schneider, Claudia, Kudla, Grzegorz, Wlotzka, Wiebke, Tuck, Alex, Tollervey, David
Format: Artigo
Language:Inglês
Published: Cell Press 2012
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3526797/
https://ncbi.nlm.nih.gov/pubmed/23000172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2012.08.013
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