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The nuclear RNA polymerase II surveillance system targets polymerase III transcripts

A key question in nuclear RNA surveillance is how target RNAs are recognized. To address this, we identified in vivo binding sites for nuclear RNA surveillance factors, Nrd1, Nab3 and the Trf4/5–Air1/2–Mtr4 polyadenylation (TRAMP) complex poly(A) polymerase Trf4, by UV crosslinking. Hit clusters wer...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Wlotzka, Wiebke, Kudla, Grzegorz, Granneman, Sander, Tollervey, David
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3102002/
https://ncbi.nlm.nih.gov/pubmed/21460797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.97
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