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A link between nuclear RNA surveillance, the human exosome and RNA polymerase II transcriptional termination

In eukaryotes, the production of mature messenger RNA that exits the nucleus to be translated into protein in the cytoplasm requires precise and extensive modification of the nascent transcript. Any failure that compromises the integrity of an mRNA may cause its retention in the nucleus and trigger...

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Détails bibliographiques
Auteurs principaux: de Almeida, Sérgio F., García-Sacristán, Ana, Custódio, Noélia, Carmo-Fonseca, Maria
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3001075/
https://ncbi.nlm.nih.gov/pubmed/20699273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq703
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