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A link between nuclear RNA surveillance, the human exosome and RNA polymerase II transcriptional termination

In eukaryotes, the production of mature messenger RNA that exits the nucleus to be translated into protein in the cytoplasm requires precise and extensive modification of the nascent transcript. Any failure that compromises the integrity of an mRNA may cause its retention in the nucleus and trigger...

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Detalhes bibliográficos
Main Authors: de Almeida, Sérgio F., García-Sacristán, Ana, Custódio, Noélia, Carmo-Fonseca, Maria
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3001075/
https://ncbi.nlm.nih.gov/pubmed/20699273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq703
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