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The THO complex cooperates with the nuclear RNA surveillance machinery to control small nucleolar RNA expression
THO is a multi-protein complex that promotes coupling between transcription and mRNA processing. In contrast to its role in mRNA biogenesis, we show here that the fission yeast THO complex negatively controls the expression of non-coding small nucleolar (sno) RNAs. Accordingly, the deletion of genes...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3488260/ https://ncbi.nlm.nih.gov/pubmed/22965128 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks838 |
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