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The nuclear RNA polymerase II surveillance system targets polymerase III transcripts

A key question in nuclear RNA surveillance is how target RNAs are recognized. To address this, we identified in vivo binding sites for nuclear RNA surveillance factors, Nrd1, Nab3 and the Trf4/5–Air1/2–Mtr4 polyadenylation (TRAMP) complex poly(A) polymerase Trf4, by UV crosslinking. Hit clusters wer...

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Detalhes bibliográficos
Main Authors: Wlotzka, Wiebke, Kudla, Grzegorz, Granneman, Sander, Tollervey, David
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3102002/
https://ncbi.nlm.nih.gov/pubmed/21460797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.97
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