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Pharmacodynamics of a New Triazole, Posaconazole, in a Murine Model of Disseminated Candidiasis
Previous in vivo studies have characterized the pharmacodynamic characteristics of two triazole compounds, fluconazole and ravuconazole. These investigations demonstrated that the 24-h area under the concentration-time curve (AUC)/MIC ratio is the critical pharmacokinetic-pharmacodynamic (PK-PD) par...
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| Autores principales: | , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society for Microbiology
2004
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC310197/ https://ncbi.nlm.nih.gov/pubmed/14693531 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.1.137-142.2004 |
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