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In Vivo Pharmacokinetics and Pharmacodynamics of a New Triazole, Voriconazole, in a Murine Candidiasis Model

In vivo studies have described the pharmacodynamic (PD) characteristics of several triazoles. These investigations have demonstrated that the 24-h area under the concentration-time curve (AUC)/MIC ratio is the critical pharmacokinetic (PK)-PD parameter associated with treatment efficacy. Further ana...

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Autores principales: Andes, D., Marchillo, K., Stamstad, T., Conklin, R.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2003
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC201151/
https://ncbi.nlm.nih.gov/pubmed/14506026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.10.3165-3169.2003
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