In Vivo Pharmacokinetics and Pharmacodynamics of a New Triazole, Voriconazole, in a Murine Candidiasis Model
In vivo studies have described the pharmacodynamic (PD) characteristics of several triazoles. These investigations have demonstrated that the 24-h area under the concentration-time curve (AUC)/MIC ratio is the critical pharmacokinetic (PK)-PD parameter associated with treatment efficacy. Further ana...
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| Udgivet i: | Antimicrob Agents Chemother |
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| Principais autores: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology (ASM)
2003
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC201151/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14506026/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.47.10.3165-3169.2003 |
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