In Vivo Pharmacokinetics and Pharmacodynamics of a New Triazole, Voriconazole, in a Murine Candidiasis Model

In vivo studies have described the pharmacodynamic (PD) characteristics of several triazoles. These investigations have demonstrated that the 24-h area under the concentration-time curve (AUC)/MIC ratio is the critical pharmacokinetic (PK)-PD parameter associated with treatment efficacy. Further ana...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Andes, D., Marchillo, K., Stamstad, T., Conklin, R.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2003
Assuntos:	Pharmacology
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC201151/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14506026/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.47.10.3165-3169.2003
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