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Pharmacodynamics of Fluconazole in a Murine Model of Systemic Candidiasis

In this study we defined the pharmacodynamic parameter that optimizes outcome in deep-seated Candida albicans infections treated with fluconazole. Using a murine model of systemic candidiasis, we conducted single-dose dose-ranging studies with fluconazole to determine the dosage of this drug that re...

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Detalhes bibliográficos
Main Authors: Louie, Arnold, Drusano, George L., Banerjee, Partha, Liu, Qing-Feng, Liu, Weiguo, Kaw, Pamela, Shayegani, Mehdi, Taber, Harry, Miller, Michael H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC105753/
https://ncbi.nlm.nih.gov/pubmed/9593135
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