Pharmacodynamics of Oritavancin (LY333328) in a Neutropenic-Mouse Thigh Model of Staphylococcus aureus Infection

The pharmacokinetics and pharmacodynamics of oritavancin (LY333328), a glycopeptide antibiotic with concentration-dependent bactericidal activity against gram-positive pathogens, in a neutropenic-mouse thigh model of Staphylococcus aureus infection were studied. Plasma radioequivalent concentrations...

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Main Authors: Boylan, Carole J., Campanale, Kristina, Iversen, Philip W., Phillips, Diane L., Zeckel, Michael L., Parr Jr., Thomas R.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2003
主題:
Experimental Therapeutics
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC153305/
https://ncbi.nlm.nih.gov/pubmed/12709343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.5.1700-1706.2003
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