Pharmacodynamics of Oritavancin (LY333328) in a Neutropenic-Mouse Thigh Model of Staphylococcus aureus Infection

The pharmacokinetics and pharmacodynamics of oritavancin (LY333328), a glycopeptide antibiotic with concentration-dependent bactericidal activity against gram-positive pathogens, in a neutropenic-mouse thigh model of Staphylococcus aureus infection were studied. Plasma radioequivalent concentrations...

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Bibliografiske detaljer

Udgivet i:	Antimicrob Agents Chemother
Principais autores:	Boylan, Carole J., Campanale, Kristina, Iversen, Philip W., Phillips, Diane L., Zeckel, Michael L., Parr Jr., Thomas R.
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 2003
Fag:	Experimental Therapeutics
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC153305/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12709343/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.47.5.1700-1706.2003
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