Pharmacodynamics of Fluconazole in a Murine Model of Systemic Candidiasis

In this study we defined the pharmacodynamic parameter that optimizes outcome in deep-seated Candida albicans infections treated with fluconazole. Using a murine model of systemic candidiasis, we conducted single-dose dose-ranging studies with fluconazole to determine the dosage of this drug that re...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Louie, Arnold, Drusano, George L., Banerjee, Partha, Liu, Qing-Feng, Liu, Weiguo, Kaw, Pamela, Shayegani, Mehdi, Taber, Harry, Miller, Michael H.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1998
Assuntos:	Experimental Therapeutics
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC105753/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9593135/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.42.5.1105
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