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Pharmacodynamics of the New Fluoroquinolone Gatifloxacin in Murine Thigh and Lung Infection Models
Gatifloxacin is a new 8-methoxy fluoroquinolone with enhanced activity against gram-positive cocci. We used the neutropenic murine thigh infection model to characterize the time course of antimicrobial activity of gatifloxacin and determine which pharmacokinetic (PK)-pharmacodynamic (PD) parameter b...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2002
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC127205/ https://ncbi.nlm.nih.gov/pubmed/12019073 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.46.6.1665-1670.2002 |
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