Pharmacodynamics of a New Triazole, Posaconazole, in a Murine Model of Disseminated Candidiasis

Previous in vivo studies have characterized the pharmacodynamic characteristics of two triazole compounds, fluconazole and ravuconazole. These investigations demonstrated that the 24-h area under the concentration-time curve (AUC)/MIC ratio is the critical pharmacokinetic-pharmacodynamic (PK-PD) par...

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Bibliografske podrobnosti

izdano v:	Antimicrob Agents Chemother
Principais autores:	Andes, D., Marchillo, K., Conklin, R., Krishna, Gopal, Ezzet, Farkad, Cacciapuoti, Anthony, Loebenberg, David
Format:	Artigo
Jezik:	Inglês
Izdano:	American Society for Microbiology (ASM) 2004
Teme:	Experimental Therapeutics
Online dostop:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC310197/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14693531/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.48.1.137-142.2004
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