STRUCTURAL BASIS FOR ALLOSTERIC REGULATION OF HUMAN RIBONUCLEOTIDE REDUCTASE BY NUCLEOTIDE-INDUCED OLIGOMERIZATION

Ribonucleotide reductase (RR) is an α(n)β(n) (RR1●RR2) complex that maintains balanced dNTP pools by reducing ribonucleoside diphosphates to deoxyribonucleoside diphosphates. RR1 is the catalytic subunit and RR2 houses the free radical required for catalysis. RR is allosterically regulated by its ac...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Fairman, James Wesley, Wijerathna, Sanath Ranjan, Ahmad, Md. Faiz, Xu, Hai, Nakano, Ryo, Jha, Shalini, Prendergast, Jay, Welin, Martin, Flodin, Susanne, Roos, Annette, Nordlund, Pär, Li, Zongli, Walz, Thomas, Dealwis, Chris Godfrey
Formato: Artigo
Idioma:Inglês
Publicado: 2011
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3101628/
https://ncbi.nlm.nih.gov/pubmed/21336276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2007
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares