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In vivo contributions of BH3-only proteins to neuronal death following seizures, ischemia, and traumatic brain injury

The Bcl-2 homology (BH) domain 3-only proteins are a proapoptotic subgroup of the Bcl-2 gene family, which regulate cell death via effects on mitochondria. The BH3-only proteins react to various cell stressors and promote cell death by binding and inactivating antiapoptotic Bcl-2 family members and...

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Detalhes bibliográficos
Main Authors: Engel, Tobias, Plesnila, Nikolaus, Prehn, Jochen H M, Henshall, David C
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3099642/
https://ncbi.nlm.nih.gov/pubmed/21364604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2011.26
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