Cylindromatosis mediates neuronal cell death in vitro and in vivo

The tumor-suppressor cylindromatosis (CYLD) is a deubiquitinating enzyme and key regulator of cell proliferation and inflammation. A genome-wide siRNA screen linked CYLD to receptor interacting protein-1 (RIP1) kinase-mediated necroptosis; however, the exact mechanisms of CYLD-mediated cell death re...

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Udgivet i:Cell Death Differ
Main Authors: Ganjam, Goutham K., Terpolilli, Nicole Angela, Diemert, Sebastian, Eisenbach, Ina, Hoffmann, Lena, Reuther, Christina, Herden, Christiane, Roth, Joachim, Plesnila, Nikolaus, Culmsee, Carsten
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6113218/
https://ncbi.nlm.nih.gov/pubmed/29352268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-017-0046-7
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