Apoptosis-Inducing Factor Triggered by Poly(ADP-Ribose) Polymerase and Bid Mediates Neuronal Cell Death after Oxygen-Glucose Deprivation and Focal Cerebral Ischemia

Delayed neuronal cell death occurring hours after reperfusion is a hallmark of ischemic stroke and a primary target for neuroprotective strategies. In the present study, we investigated whether apoptosis-inducing factor (AIF), a caspase-independent proapoptotic protein, is responsible for neuronal c...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Culmsee, Carsten, Zhu, Changlian, Landshamer, Stefan, Becattini, Barbara, Wagner, Ernst, Pellecchia, Maurizio, Blomgren, Klas, Plesnila, Nikolaus
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2005
Assuntos:
Neurobiology of Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6725791/
https://ncbi.nlm.nih.gov/pubmed/16267234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2818-05.2005
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