BH3-only proteins BIM and PUMA in the regulation of survival and neuronal differentiation of newly generated cells in the adult mouse hippocampus

Neurogenesis persists in the adult hippocampus, where several thousand neurons are born every day. Most of the newly generated cells are eliminated by apoptosis, possibly because of their failure to integrate properly into neural networks. The BH3-only proteins Bim and Puma have been shown to mediat...

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Detalhes bibliográficos
Main Authors: Bunk, E C, König, H-G, Bernas, T, Engel, T, Henshall, D C, Kirby, B P, Prehn, J H M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3039291/
https://ncbi.nlm.nih.gov/pubmed/21364616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2009.13
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