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Wild-type and A315T mutant TDP-43 exert differential neurotoxicity in a Drosophila model of ALS
The RNA-binding protein TDP-43 has been linked to amyotrophic lateral sclerosis (ALS) both as a causative locus and as a marker of pathology. With several missense mutations being identified within TDP-43, efforts have been directed towards generating animal models of ALS in mouse, zebrafish, Drosop...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3098735/ https://ncbi.nlm.nih.gov/pubmed/21441568 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddr124 |
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