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Identification of Genetic Modifiers of TDP-43 Neurotoxicity in Drosophila
Cytosolic aggregation of the nuclear RNA-binding protein TDP-43 is a histopathologic signature of degenerating neurons in amyotrophic lateral sclerosis (ALS), and mutations in the TARDBP gene encoding TDP-43 cause dominantly inherited forms of this condition. To understand the relationship between T...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3584124/ https://ncbi.nlm.nih.gov/pubmed/23468938 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0057214 |
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