Motor neurons and glia exhibit specific individualized responses to TDP-43 expression in a Drosophila model of amyotrophic lateral sclerosis

Amyotrophic lateral sclerosis (ALS) is a fatal disease characterized by complex neuronal and glial phenotypes. Recently, RNA-based mechanisms have been linked to ALS via RNA-binding proteins such as TDP-43, which has been studied in vivo using models ranging from yeast to rodents. We have developed...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Estes, Patricia S., Daniel, Scott G., Mccallum, Abigail P., Boehringer, Ashley V., Sukhina, Alona S., Zwick, Rebecca A., Zarnescu, Daniela C.
Format: Artigo
Langue:Inglês
Publié: The Company of Biologists Limited 2013
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3634655/
https://ncbi.nlm.nih.gov/pubmed/23471911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.010710
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