Motor neurons and glia exhibit specific individualized responses to TDP-43 expression in a Drosophila model of amyotrophic lateral sclerosis

Amyotrophic lateral sclerosis (ALS) is a fatal disease characterized by complex neuronal and glial phenotypes. Recently, RNA-based mechanisms have been linked to ALS via RNA-binding proteins such as TDP-43, which has been studied in vivo using models ranging from yeast to rodents. We have developed...

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Bibliografiska uppgifter
Huvudupphovsmän: Estes, Patricia S., Daniel, Scott G., Mccallum, Abigail P., Boehringer, Ashley V., Sukhina, Alona S., Zwick, Rebecca A., Zarnescu, Daniela C.
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Company of Biologists Limited 2013
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3634655/
https://ncbi.nlm.nih.gov/pubmed/23471911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.010710
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