Population pharmacokinetics of artesunate and dihydroartemisinin in pregnant and non-pregnant women with malaria

BACKGROUND: The World Health Organization endorses the use of artemisinin-based combination therapy for treatment of acute uncomplicated falciparum malaria in the second and third trimesters of pregnancy. However, the effects of pregnancy on the pharmacokinetics of artemisinin derivatives, such as a...

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Détails bibliographiques
Auteurs principaux: Morris, Carrie A, Onyamboko, Marie A, Capparelli, Edmund, Koch, Matthew A, Atibu, Joseph, Lokomba, Vicky, Douoguih, Macaya, Hemingway-Foday, Jennifer, Wesche, David, Ryder, Robert W, Bose, Carl, Wright, Linda, Tshefu, Antoinette K, Meshnick, Steven, Fleckenstein, Lawrence
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2011
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3098207/
https://ncbi.nlm.nih.gov/pubmed/21548983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-10-114
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