Pharmacokinetics and pharmacodynamics of artesunate and dihydroartemisinin following oral treatment in pregnant women with asymptomatic Plasmodium falciparum infections in Kinshasa DRC

BACKGROUND: In many malaria-endemic countries, increasing resistance may soon compromise the efficacy of sulphadoxine-pyrimethamine (SP) for intermittent preventative treatment (IPT) of malaria in pregnancy. Artemisinin-based IPT regimens represent a promising potential alternative to SP. Pharmacoki...

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Hlavní autoři: Onyamboko, Marie A, Meshnick, Steven R, Fleckenstein, Lawrence, Koch, Matthew A, Atibu, Joseph, Lokomba, Victor, Douoguih, Macaya, Hemingway-Foday, Jennifer, Wesche, David, Ryder, Robert W, Bose, Carl, Wright, Linda L, Tshefu, Antoinette K, Capparelli, Edmund V
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2011
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3056842/
https://ncbi.nlm.nih.gov/pubmed/21352601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-10-49
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