Population Pharmacokinetics of Telapristone (CDB-4124) and its Active Monodemethylated Metabolite CDB-4453, with a Mixture Model for Total Clearance

Por Morris, Denise, Podolski, Joseph, Kirsch, Alan, Wiehle, Ronald, Fleckenstein, Lawrence
Publicado em 2011

The Importance of Including Topics Related to Pharmacogenetics, Pharmacogenomics, and Medical Genetics in the Pharmacy Curriculum

Por Harirforoosh, Sam, Fleckenstein, Lawrence, Mahajan, Pramod, Aruoma, Okezie I., Huang, Ying, Moridani, Majid
Publicado em 2009

Fatal Outcome of Disseminated Strongyloidiasis despite Detectable Plasma and Cerebrospinal Levels of Orally Administered Ivermectin

Por Rose, Charles E., Paciullo, Christopher A., Kelly, David R., Dougherty, Mark J., Fleckenstein, Lawrence L.
Publicado em 2009

Review of the clinical pharmacokinetics of artesunate and its active metabolite dihydroartemisinin following intravenous, intramuscular, oral or rectal administration

Por Morris, Carrie A, Duparc, Stephan, Borghini-Fuhrer, Isabelle, Jung, Donald, Shin, Chang-Sik, Fleckenstein, Lawrence
Publicado em 2011

Failure of Ivermectin per Rectum to Achieve Clinically Meaningful Serum Levels in Two Cases of Strongyloides Hyperinfection

Por Bogoch, Isaac I., Khan, Kamran, Abrams, Howard, Nott, Caroline, Leung, Elizabeth, Fleckenstein, Lawrence, Keystone, Jay S.
Publicado no Am J Trop Med Hyg (2015)

Effects of Body Size and Gender on the Population Pharmacokinetics of Artesunate and Its Active Metabolite Dihydroartemisinin in Pediatric Malaria Patients

Por Morris, Carrie A., Tan, Beesan, Duparc, Stephan, Borghini-Fuhrer, Isabelle, Jung, Donald, Shin, Chang-Sik, Fleckenstein, Lawrence
Publicado em 2013

AAPS–FIP Summary Workshop Report: Pharmacogenetics in Individualized Medicine: Methods, Regulatory, and Clinical Applications

Por Moridani, Majid, Maitland-van der Zee, Anke-Hilse, Sasaki, Hitoshi, McKinnon, Ross, Fleckenstein, Lawrence, Shah, Vinod P.
Publicado em 2009

Excretion of Moxidectin into Breast Milk and Pharmacokinetics in Healthy Lactating Women

Por Korth-Bradley, Joan M., Parks, Virginia, Chalon, Stephan, Gourley, Ian, Matschke, Kyle, Gossart, Sophie, Bryson, Philip, Fleckenstein, Lawrence
Publicado em 2011

The Effect of a High-Fat Breakfast on the Pharmacokinetics of Moxidectin in Healthy Male Subjects: A Randomized Phase I Trial

Por Korth-Bradley, Joan M., Parks, Virginia, Chalon, Stephan, Gourley, Ian, Matschke, Kyle, Cailleux, Karine, Fitoussi, Serge, Fleckenstein, Lawrence
Publicado em 2012

Safety and efficacy of pyronaridine-artesunate in uncomplicated acute malaria: an integrated analysis of individual patient data from six randomized clinical trials

Por Duparc, Stephan, Borghini-Fuhrer, Isabelle, Craft, Carl J, Arbe-Barnes, Sarah, Miller, Robert M, Shin, Chang-Sik, Fleckenstein, Lawrence
Publicado em 2013

UMF-078: A modified flubendazole with potent macrofilaricidal activity against Onchocerca ochengi in African cattle

Por deC Bronsvoort, Barend M, Makepeace, Benjamin L, Renz, Alfons, Tanya, Vincent N, Fleckenstein, Lawrence, Ekale, David, Trees, Alexander J
Publicado em 2008

Population pharmacokinetics of artesunate and dihydroartemisinin following single- and multiple-dosing of oral artesunate in healthy subjects

Por Tan, Beesan, Naik, Himanshu, Jang, In-Jin, Yu, Kyung-Sang, Kirsch, Lee E, Shin, Chang-Sik, Craft, J Carl, Fleckenstein, Lawrence
Publicado em 2009

Non-Oral Treatment with Ivermectin for Disseminated Strongyloidiasis

Por Fusco, Dahlene N., Downs, Jennifer A., Satlin, Michael J., Pahuja, Meera, Ramos, Liz, Barie, Philip S., Fleckenstein, Lawrence, Murray, Henry W.
Publicado em 2010

Population Pharmacokinetics of Pyronaridine in Pediatric Malaria Patients

Por Ayyoub, Amal, Methaneethorn, Janthima, Ramharter, Michael, Djimde, Abdoulaye A., Tekete, Mamadou, Duparc, Stephan, Borghini-Fuhrer, Isabelle, Shin, Jang-Sik, Fleckenstein, Lawrence
Publicado no Antimicrob Agents Chemother (2016)

Review of pyronaridine anti-malarial properties and product characteristics

Por Croft Simon L, Duparc Stephan, Arbe-Barnes Sarah J, Craft J, Shin Chang-Sik, Fleckenstein Lawrence, Borghini-Fuhrer Isabelle, Rim Han-Jong
Publicado em 2012-08-01

Drug-Drug Interaction Analysis of Pyronaridine/Artesunate and Ritonavir in Healthy Volunteers

Por Morris, Carrie A., Lopez-Lazaro, Luis, Jung, Donald, Methaneethorn, Janthima, Duparc, Stephan, Borghini-Fuhrer, Isabelle, Pokorny, Rolf, Shin, Chang-Sik, Fleckenstein, Lawrence
Publicado em 2012

Review of pyronaridine anti-malarial properties and product characteristics

Por Croft, Simon L, Duparc, Stephan, Arbe-Barnes, Sarah J, Craft, J Carl, Shin, Chang-Sik, Fleckenstein, Lawrence, Borghini-Fuhrer, Isabelle, Rim, Han-Jong
Publicado em 2012

Pharmacokinetic Interaction between Pyronaridine-Artesunate and Metoprolol

Por Morris, Carrie A., Pokorny, Rolf, Lopez-Lazaro, Luis, Miller, Robert M., Arbe-Barnes, Sarah, Duparc, Stephan, Borghini-Fuhrer, Isabelle, Shin, Jang-Sik, Fleckenstein, Lawrence
Publicado em 2014

Pyronaridine-Artesunate versus Chloroquine in Patients with Acute Plasmodium vivax Malaria: A Randomized, Double-Blind, Non-Inferiority Trial

Por Poravuth, Yi, Socheat, Duong, Rueangweerayut, Ronnatrai, Uthaisin, Chirapong, Pyae Phyo, Aung, Valecha, Neena, Rao, B. H. Krishnamoorthy, Tjitra, Emiliana, Purnama, Asep, Borghini-Fuhrer, Isabelle, Duparc, Stephan, Shin, Chang-Sik, Fleckenstein, Lawrence
Publicado em 2011

Pharmacokinetics and pharmacodynamics of artesunate and dihydroartemisinin following oral treatment in pregnant women with asymptomatic Plasmodium falciparum infections in Kinshasa...

Por Onyamboko, Marie A, Meshnick, Steven R, Fleckenstein, Lawrence, Koch, Matthew A, Atibu, Joseph, Lokomba, Victor, Douoguih, Macaya, Hemingway-Foday, Jennifer, Wesche, David, Ryder, Robert W, Bose, Carl, Wright, Linda L, Tshefu, Antoinette K, Capparelli, Edmund V
Publicado em 2011