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Pharmacokinetic Interaction between Pyronaridine-Artesunate and Metoprolol
The objectives of this study were to characterize any drug-drug interaction between the antimalarial Pyramax (pyronaridine-artesunate [PA]) and the CYP2D6 probe substrate metoprolol and to assess the safety of 60-day or 90-day PA redosing, particularly with regard to liver biochemistry parameters. H...
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| Autori principali: | , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Microbiology
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4187956/ https://ncbi.nlm.nih.gov/pubmed/25070091 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02716-14 |
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