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Effects of Body Size and Gender on the Population Pharmacokinetics of Artesunate and Its Active Metabolite Dihydroartemisinin in Pediatric Malaria Patients

Despite the important role of the antimalarial artesunate and its active metabolite dihydroartemisinin (DHA) in malaria treatment efforts, there are limited data on the pharmacokinetics of these agents in pediatric patients. This study evaluated the effects of body size and gender on the pharmacokin...

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Detalles Bibliográficos
Main Authors: Morris, Carrie A., Tan, Beesan, Duparc, Stephan, Borghini-Fuhrer, Isabelle, Jung, Donald, Shin, Chang-Sik, Fleckenstein, Lawrence
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3837878/
https://ncbi.nlm.nih.gov/pubmed/24041884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00635-13
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