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Review of the clinical pharmacokinetics of artesunate and its active metabolite dihydroartemisinin following intravenous, intramuscular, oral or rectal administration

Artesunate (AS) is a clinically versatile artemisinin derivative utilized for the treatment of mild to severe malaria infection. Given the therapeutic significance of AS and the necessity of appropriate AS dosing, substantial research has been performed investigating the pharmacokinetics of AS and i...

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Detaylı Bibliyografya
Asıl Yazarlar: Morris, Carrie A, Duparc, Stephan, Borghini-Fuhrer, Isabelle, Jung, Donald, Shin, Chang-Sik, Fleckenstein, Lawrence
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2011
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3180444/
https://ncbi.nlm.nih.gov/pubmed/21914160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-10-263
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