The pharmacokinetic properties of intramuscular artesunate and rectal dihydroartemisinin in uncomplicated falciparum malaria

AIMS: To obtain pharmacokinetic data for artesunate (ARTS) and its active metabolite dihydroartemisinin (DHA) following i.m. ARTS and rectal DHA administration. METHODS: Twelve Vietnamese patients with uncomplicated falciparum malaria were randomized to receive either i.v. or i.m. ARTS (120 mg), wit...

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Detalhes bibliográficos
Main Authors: Ilett, Kenneth F, Batty, Kevin T, Powell, Shane M, Binh, Tran Quang, Thu, Le Thi Anh, Phuong, Hoang Lan, Hung, Nguyen Canh, Davis, Timothy M E
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2002
Assuntos:
Pharmacokinetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1874553/
https://ncbi.nlm.nih.gov/pubmed/11849191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.0306-5251.2001.01519.x
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