A pharmacokinetic and pharmacodynamic study of intravenous vs oral artesunate in uncomplicated falciparum malaria

AIMS: To obtain comprehensive pharmacokinetic and pharmacodynamic data for artesunate (ARTS) and its active metabolite dihydroartemisinin (DHA) following i.v. and oral administration of ARTS to patients with acute, uncomplicated falciparum malaria. METHODS: Twenty-six Vietnamese patients with falcip...

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Autori principali: Batty, Kevin T, Anh Thu, Le Thi, Davis, Timothy M E, Ilett, Kenneth F, Xuan Mai, Truong, Canh Hung, Nguyen, Phuc Tien, Nguyen, Powell, Shane M, Van Thien, Huynh, Quang Binh, Tran, Kim, Nguyen Van
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 1998
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Original Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1873351/
https://ncbi.nlm.nih.gov/pubmed/9491824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.1998.00655.x
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