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The Effect of a High-Fat Breakfast on the Pharmacokinetics of Moxidectin in Healthy Male Subjects: A Randomized Phase I Trial

The objective of this study was to assess the effect of a high-fat meal on the pharmacokinetics of moxidectin. Healthy male subjects were randomized to receive single oral 8 mg doses of moxidectin after an overnight fast or high-fat breakfast. In fasted subjects (N = 27), mean [SD] parameters were C...

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Detalhes bibliográficos
Main Authors: Korth-Bradley, Joan M., Parks, Virginia, Chalon, Stephan, Gourley, Ian, Matschke, Kyle, Cailleux, Karine, Fitoussi, Serge, Fleckenstein, Lawrence
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society of Tropical Medicine and Hygiene 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3247120/
https://ncbi.nlm.nih.gov/pubmed/22232462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4269/ajtmh.2012.11-0415
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