Tigecycline Does Not Prolong Corrected QT Intervals in Healthy Subjects

We evaluated the effect of tigecycline (50-mg and 200-mg doses) on corrected QT (QTc) intervals and assessed safety and tolerability in a randomized, placebo-controlled, four-period crossover study of 48 (44 male) healthy volunteers aged 22 to 53 years. Fed subjects received tigecycline (50 mg or 20...

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Bibliografiske detaljer
Main Authors: Korth-Bradley, Joan M., McGovern, Paul C., Salageanu, Joanne, Matschke, Kyle, Plotka, Anna, Pawlak, Sylvester
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2013
Fag:
Clinical Therapeutics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3623319/
https://ncbi.nlm.nih.gov/pubmed/23403419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01576-12
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