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The effect of tafamidis on the QT(c) interval in healthy subjects

AIMS: The transthyretin (TTR) stabilizer, tafamidis, has demonstrated efficacy and safety in the treatment of TTR familial amyloid polyneuropathy (20 mg day(−1)). Tafamidis use in TTR cardiomyopathy led to the study of the potential effect of tafamidis on the QT(c) interval in healthy subjects. METH...

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Publicat a:Br J Clin Pharmacol
Autors principals: Klamerus, Karen J, Watsky, Eric, Moller, Robert, Wang, Ronnie, Riley, Steve
Format: Artigo
Idioma:Inglês
Publicat: BlackWell Publishing Ltd 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4456124/
https://ncbi.nlm.nih.gov/pubmed/25546001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12561
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